Chemical compounds are needed in all areas of life to solve the challenges of our time. From materials to combat climate change to the production of new active ingredients, many solution strategies rely on the availability of molecules with suitable properties. ChemASAP aims to provide chemical compounds that are designed to suit the diverse applications of researchers at KIT (and beyond). We want to accelerate science through straightforward synthesis and analysis of molecular building blocks. We bring in our expertise as chemists to prepare and analyze single compounds or compound libraries.

ChemASAP is made up of components, each of which allows precisely tailored processes for chemical reaction control and analysis of the resulting compounds. All work is carried out with the aim of fully automated process control. For this purpose, systems from commercial suppliers were integrated and systems were constructed in-house. We build those components in-house for which there are no commercial solutions to date or which only allow the necessary tasks to be performed to a limited degree of satisfaction. We develop in the hope of supporting other groups and projects and showing ways in which other scientists can also make automation strategies possible. Our work is available as open hardware and open software and the team is looking forward to future collaborations.

ChemASAP represents a cutting-edge model instance offering seamless access to fully digitized chemical reaction and characterization data. Operating as a fully automated platform, all procedures are meticulously planned, executed, and documented digitally, thus circumventing any digital interruptions. To facilitate this, chemical reactions are presented in a machine-readable format, while measurement data essential for characterizing the resulting molecules is seamlessly funneled into databases, enabling AI-supported data analysis. Our team is committed to advancing scientific progress through the systematic integration of digitalization strategies. We aspire to support the scientific community by continually enhancing and expanding the repertoire of available tools for digital methodologies.

The ChemASAP team is committed to openly providing research data whenever possible and appropriate. The research data obtained will be made publicly accessible through the Chemotion research data repository (in coordination with research partners). We aim to support other scientists by making data available. The combination of high throughput with automated checks provides an opportunity to build databases with a broad scientific profile. We aim to set an example in providing transparent, reproducible, and reusable data to advance chemical research for ourselves and others.